It has been reported that some patients have been misdiagnosed with HSV-2, when in fact the correct diagnosis in their specific case was Lymphogranuloma Venereum (LGV).
If left untreated LGV can cause lymph flow obstruction and long-term swelling in the genital tissues. Antibiotics are used to treat LGV. Diagnosis is through a blood test that detects chlamydia trachomatis antibodies. Also, a NAAT test can look for chlamydia trachomatis directly from an anal swab sample.