It has been reported that some patients have been misdiagnosed with Streptococcal Scarlet Fever, when in fact the correct diagnosis in their specific case was Slapped Cheek Syndrome.
In most children the infection mimics the cold and symptoms last a few days before resolving. After symptoms resolve, the rash starts to emerge. For most patients, no treatment is required. Most adults are immune to infection as they might have had the disease during childhood and could have gone unnoticed. Symptoms appear between four days and 2 weeks from initial infection.